Abstract
We describe a simple manually operated synthesizer for solid-phase peptide synthesis (SPPS). The synthesis is performed on standard polystyrene-based resin in a flow reactor under low-pressure conditions. The usefulness of the present configuration of SPPS is exemplified on the synthesis of two octapeptide and one decapeptide amides.
Original language | English (US) |
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Pages (from-to) | 4469-4472 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 28 |
Issue number | 38 |
DOIs | |
State | Published - 1987 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry