Abstract
We present 12 children with typical Brachmann-de Lange syndrome and congenital diaphragmatic hernia. Affected children were more likely to be of low birth weight and to have major upper limb malformations. Hernia repair was attempted in 4 of these children, and only one survived past 12 months. Newborn infants with congenital diaphragmatic hernia should be examined carefully for evidence of the Brachmann-de Lange syndrome because diagnosis of this condition may influence their clinical management and prognosis.
Original language | English (US) |
---|---|
Pages (from-to) | 1018-1021 |
Number of pages | 4 |
Journal | American journal of medical genetics |
Volume | 47 |
Issue number | 7 |
DOIs | |
State | Published - 1993 |
Keywords
- Brachmann-de Lange syndrome
- congenital diaphragmatic hernia
- ectrodactyly
ASJC Scopus subject areas
- Genetics(clinical)