We present 12 children with typical Brachmann-de Lange syndrome and congenital diaphragmatic hernia. Affected children were more likely to be of low birth weight and to have major upper limb malformations. Hernia repair was attempted in 4 of these children, and only one survived past 12 months. Newborn infants with congenital diaphragmatic hernia should be examined carefully for evidence of the Brachmann-de Lange syndrome because diagnosis of this condition may influence their clinical management and prognosis.
|Original language||English (US)|
|Number of pages||4|
|Journal||American journal of medical genetics|
|State||Published - 1993|
- Brachmann-de Lange syndrome
- congenital diaphragmatic hernia
ASJC Scopus subject areas