Conformational determinants of agonist versus antagonist properties of [D-Pen²,D-Pen⁵]enkephalin (DPDPE) analogs at opioid receptors. Comparison of X-ray crystallographic structure, solution ¹H NMR data, and molecular dynamic simulations of [L-Ala³]DPDPE and [D-Ala³]DPDPE

Nathan Collins, Judith L. Flippen-Anderson, Ronald C. Haaseth, Jeffery R. Deschamps, Clifford George, Katalin Kövér, Victor J. Hruby

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

CCDC 123686: Experimental Crystal Structure Determination
Collins, N. (Creator), Flippen-Anderson, J. L. (Creator), Haaseth, R. C. (Creator), Deschamps, J. R. (Creator), George, C. (Creator), Kövér, K. (Contributor) & Hruby, V. J. (Creator), Cambridge Crystallographic Data Centre, 1996
DOI: 10.5517/cc44pwt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc44pwt&sid=DataCite
Dataset
CCDC 123687: Experimental Crystal Structure Determination
Collins, N. (Creator), Flippen-Anderson, J. L. (Creator), Haaseth, R. C. (Creator), Deschamps, J. R. (Creator), George, C. (Creator), Kövér, K. (Contributor) & Hruby, V. J. (Creator), Cambridge Crystallographic Data Centre, 1996
DOI: 10.5517/cc44pxv, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc44pxv&sid=DataCite
Dataset

Conformational determinants of agonist versus antagonist properties of [D-Pen2,D-Pen5]enkephalin (DPDPE) analogs at opioid receptors. Comparison of X-ray crystallographic structure, solution 1H NMR data, and molecular dynamic simulations of [L-Ala3]DPDPE and [D-Ala3]DPDPE