Confocal microendoscope for use in a clinical setting

Joshua A. Udovich, Andy R. Rouse, Anthony Tanbakuchi, Molly A. Brewer, Richard Sampliner, Arthur F. Gmitro

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations


A mobile confocal microendoscope for use in a clinical setting has been developed. This system employs an endoscope consisting of a custom designed objective lens with a fiber optic imaging bundle to collect in-vivo images of patients. Some highlights and features of this mobile system include frame rates of up to 30 frames per second, an automated focus mechanism, automated dye delivery, clinician control, and the ability to be used in an area where there is a single 110V outlet. All optics are self-contained and the entire enclosure and catheter can be moved between surgical suites, sterilized and brought online in under 15 minutes. At this time, all data have been collected with a 488 nm laser, but the system is able to have a second laser line added to provide additional imaging capability. Preliminary in vivo results of images from the ovaries using topical fluorescein as a contrast agent are shown. Future plans for the system include use of acridine orange (AO) or SYTO-16 as a nucleic acid stain.

Original languageEnglish (US)
Title of host publicationEndoscopic Microscopy II
StatePublished - 2007
EventEndoscopic Microscopy II - San Jose, CA, United States
Duration: Jan 21 2007Jan 23 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherEndoscopic Microscopy II
Country/TerritoryUnited States
CitySan Jose, CA


  • Confocal
  • Endoscope
  • Fiber
  • Fluorescence
  • Imaging
  • Microscopy
  • Optics
  • Tissue

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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