Con A induced suppressor cells: Suppression with I region incompatibility

Elizabeth Dugan, John E. Niederhuber, J. A. Frelinger, Laura Mayo, D. C. Shreffler

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Allogeneic Con A induced suppressor cells differing in the I and S region but not H-2K or H-2D regions were as efficient as syngeneic cells in suppressing the secondary IgM and IgG response to burro erythrocytes. Con A activated suppressor cells were not sensitive to anti-Ia serum and complement. However, if the spleen cell population was treated with anti-Ia serum and complement before stimulation with Con A, suppressor cells were not generated.

Original languageEnglish (US)
Pages (from-to)322-330
Number of pages9
JournalCellular Immunology
Issue number2
StatePublished - Mar 15 1977

ASJC Scopus subject areas

  • Immunology


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