TY - JOUR
T1 - Computerized 3-dimensional localization of a video capsule in the abdominal cavity
T2 - Validation by digital radiography
AU - Marya, Neil
AU - Karellas, Andrew
AU - Foley, Anne
AU - Roychowdhury, Abhijit
AU - Cave, David
N1 - Funding Information:
DISCLOSURE: The following author disclosed financial relationships relevant to this publication: Dr Cave is a consultant to Olympus Medical Systems and Capso Vision. All other authors disclosed no financial relationships relevant to this publication. This study was supported by Olympus, Tokyo, Japan.
PY - 2014/4
Y1 - 2014/4
N2 - Background Wireless video capsule endoscopy allows the noninvasive visualization of the small intestine. Currently, capsules do not provide localization information while traversing the GI tract. Objective To report on the radiological validation of 3-dimensional localization software incorporated in a newly developed capsule. By using radiofrequency transmission, the software measures the strength of the capsule's signal to locate the position of the capsule. Setting This study was performed at the University of Massachusetts Medical Center, Worcester, Mass. Patients Thirty healthy volunteers consented to the experimental procedure. Design After ingestion of the capsule, subjects had 5 sets of anteroposterior and lateral radiographs taken every 30 minutes while the software calculated the position of the capsule. By using the radiographs, we calculated the location of the capsule in the abdominal cavity and compared the results with those generated by the software. Results Average error (and standard deviation) among the 3-dimensional coordinates was X, 2.00 cm (1.64); Y, 2.64 cm (2.39); and Z, 2.51 cm (1.83). The average total spatial error among all measurements was 13.26 cm3 (22.72). There was a correlation between increased subject body mass index and the 3-dimensional software measurement error. Limitations This study was performed in healthy volunteers and needs further validation in patients with small intestinal disorders. Conclusions The new 3-dimensional software provides localization of the capsule consistent with radiological observations. However, further validation of the software's clinical utility is required with a prospective clinical trial.
AB - Background Wireless video capsule endoscopy allows the noninvasive visualization of the small intestine. Currently, capsules do not provide localization information while traversing the GI tract. Objective To report on the radiological validation of 3-dimensional localization software incorporated in a newly developed capsule. By using radiofrequency transmission, the software measures the strength of the capsule's signal to locate the position of the capsule. Setting This study was performed at the University of Massachusetts Medical Center, Worcester, Mass. Patients Thirty healthy volunteers consented to the experimental procedure. Design After ingestion of the capsule, subjects had 5 sets of anteroposterior and lateral radiographs taken every 30 minutes while the software calculated the position of the capsule. By using the radiographs, we calculated the location of the capsule in the abdominal cavity and compared the results with those generated by the software. Results Average error (and standard deviation) among the 3-dimensional coordinates was X, 2.00 cm (1.64); Y, 2.64 cm (2.39); and Z, 2.51 cm (1.83). The average total spatial error among all measurements was 13.26 cm3 (22.72). There was a correlation between increased subject body mass index and the 3-dimensional software measurement error. Limitations This study was performed in healthy volunteers and needs further validation in patients with small intestinal disorders. Conclusions The new 3-dimensional software provides localization of the capsule consistent with radiological observations. However, further validation of the software's clinical utility is required with a prospective clinical trial.
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U2 - 10.1016/j.gie.2013.11.022
DO - 10.1016/j.gie.2013.11.022
M3 - Article
C2 - 24424401
AN - SCOPUS:84896389179
SN - 0016-5107
VL - 79
SP - 669
EP - 674
JO - Gastrointestinal endoscopy
JF - Gastrointestinal endoscopy
IS - 4
ER -