Computational and biophysical determination of pathogenicity of variants of unknown significance in cardiac thin filament

Biochemistry, Genetics and Molecular Biology

• Dynamics 100%
• Protein Filament 50%
• Genetics 50%
• Genotyping 50%
• Point Mutation 50%
• Tropomyosin 50%
• Troponin T 50%
• Cardiac Troponin 50%
• Differential Scanning Calorimetry 50%

Keyphrases

• Variant Reclassification 33%
• Experimental Correlation 33%
• Structure of Affect 33%