Complete resolution of paget disease of the vulva with imiquimod cream

Kenneth D. Hatch; John R. Davis

doi:10.1097/LGT.0b013e31815a58a5

Complete resolution of paget disease of the vulva with imiquimod cream

Kenneth D. Hatch, John R. Davis

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

Extra mammary Paget disease (EMPD) is a neoplastic disease of apocrine gland bearing skin. Surgical excision is the standard of care for EMPD; however, it is accompanied by recurrence in more than 60% of the patients. Recently, imiquimod cream has been reported to induce complete responses in primary or recurrent EMPD. We report on 2 women with vulva EMPD who achieved biopsy-confirmed resolution of their disease after topical application of imiquimod 5% cream.

Original language	English (US)
Pages (from-to)	90-94
Number of pages	5
Journal	Journal of Lower Genital Tract Disease
Volume	12
Issue number	2
DOIs	https://doi.org/10.1097/LGT.0b013e31815a58a5
State	Published - Apr 2008

Keywords

Imiquimod
Paget disease
Vulva

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1097/LGT.0b013e31815a58a5

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abstract = "Extra mammary Paget disease (EMPD) is a neoplastic disease of apocrine gland bearing skin. Surgical excision is the standard of care for EMPD; however, it is accompanied by recurrence in more than 60% of the patients. Recently, imiquimod cream has been reported to induce complete responses in primary or recurrent EMPD. We report on 2 women with vulva EMPD who achieved biopsy-confirmed resolution of their disease after topical application of imiquimod 5% cream.",

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AB - Extra mammary Paget disease (EMPD) is a neoplastic disease of apocrine gland bearing skin. Surgical excision is the standard of care for EMPD; however, it is accompanied by recurrence in more than 60% of the patients. Recently, imiquimod cream has been reported to induce complete responses in primary or recurrent EMPD. We report on 2 women with vulva EMPD who achieved biopsy-confirmed resolution of their disease after topical application of imiquimod 5% cream.

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Complete resolution of paget disease of the vulva with imiquimod cream

Abstract

Keywords

ASJC Scopus subject areas

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