Comparison of Serum Per- and Polyfluoroalkyl Substances Concentrations in Incumbent and Recruit Firefighters and Longitudinal Assessment in Recruits

Amy J. Nematollahi, Julia Marie Fisher, Melissa A. Furlong, Paloma I. Beamer, Jaclyn M. Goodrich, Judith M. Graber, Antonia M. Calafat, Julianne Cook Botelho, Shawn C. Beitel, Sally R. Littau, John J. Gulotta, Darin D. Wallentine, Jefferey L Burgess

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Objective: Firefighters are occupationally exposed to per- and polyfluoroalkyl substances (PFAS). This study objective was to compare serum PFAS concentrations in incumbent and recruit firefighters and evaluate temporal trends among recruits. Methods: SerumPFAS concentrations weremeasured in 99 incumbent and 55 recruit firefighters at enrollment in 2015-2016, with follow-up 20 to 37 months later for recruits. Linear and logistic regression and linear mixed-effects models were used for analyses. Fireground exposure impact on PFAS concentrations was investigated using adjusted linear and logistic regression models. Results: Incumbents had lower n-PFOA and PFNA than recruits and most PFAS significantly decreased over time among male recruits. No significant links were found between cumulative fireground exposures and PFAS concentrations. Conclusions: Serum PFAS concentrations were not increased in incumbent firefighters compared with recruits and were not associated with cumulative fireground exposures.

Original languageEnglish (US)
Pages (from-to)202-211
Number of pages10
JournalJournal of occupational and environmental medicine
Volume66
Issue number3
DOIs
StatePublished - Mar 1 2024

Keywords

  • PFAS
  • vulnerable occupations
  • workplace exposures

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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