Comparison of micro-optic systems for close-focus microendoscopic applications

Dominique Galvez, Zhihan Hong, Andrew D. Rocha, Rongguang Liang, Jennifer K Barton

Research output: Chapter in Book/Report/Conference proceedingConference contribution


To detect disease in organs with small lumens like the pancreas or fallopian tubes, where lumens may be collapsed or filled with mucus, cilia, or plicae, minimally invasive submillimeter endoscopes must meet unique optical requirements. They must provide a moderate angular field of view (AFOV), a close working distance (WD), and provide adequate resolution for the application. Additionally, when using miniature fiber bundles for image relay, the effect of the honeycomb pattern and potential fiber crosstalk must be considered. We compare the optical performance of a gradient refractive index (GRIN) singlet, a 3D-printed doublet, and a 3D-printed triplet, as well as discuss the consequences of fiber bundle use. We show that for our designs, both GRIN lenses and 3D printed aspheric lens systems can meet our application requirements, with to the ability to resolve less than 10μm at 10% contrast. The effect of fiber bundle crosstalk is shown to be negligible because of limited mode coupling in realistic manufactured fiber bundles.

Original languageEnglish (US)
Title of host publicationEndoscopic Microscopy XIX
EditorsGuillermo J. Tearney, Thomas D. Wang, Melissa J. Suter
ISBN (Electronic)9781510668997
StatePublished - 2024
EventEndoscopic Microscopy XIX 2024 - San Francisco, United States
Duration: Jan 27 2024Jan 28 2024

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceEndoscopic Microscopy XIX 2024
Country/TerritoryUnited States
CitySan Francisco


  • 3D-printed optics
  • fiber bundle
  • micro-optics
  • Microendoscopy
  • miniature optics
  • two-photon polymerization

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Comparison of micro-optic systems for close-focus microendoscopic applications'. Together they form a unique fingerprint.

Cite this