TY - JOUR
T1 - Comparison of critical drug-drug interaction listings
T2 - The department of veterans affairs medical system and standard reference compendia
AU - Olvey, E. L.
AU - Clauschee, S.
AU - Malone, D. C.
PY - 2010/1
Y1 - 2010/1
N2 - The objective of this study was to evaluate the agreement among the US Department of Veterans Affairs (VA) listing of criticaĺ drug-drug interactions (DDIs) and two standard drug-interaction compendia. A list of critical DDIs, as defined by the VA, was compared with two standard commercially available compendia (Micromedex DRUG-REAX and Drug Interactions: Analysis and Management (DIAM)) in order to determine the level of agreement among the systems. Of 982 DDIs classified as critical by the VA, only 136 DDIs (13.7%) were considered critical in all three systems. Our conclusion was that, overall, there is poor agreement among the compendia and the VA system.
AB - The objective of this study was to evaluate the agreement among the US Department of Veterans Affairs (VA) listing of criticaĺ drug-drug interactions (DDIs) and two standard drug-interaction compendia. A list of critical DDIs, as defined by the VA, was compared with two standard commercially available compendia (Micromedex DRUG-REAX and Drug Interactions: Analysis and Management (DIAM)) in order to determine the level of agreement among the systems. Of 982 DDIs classified as critical by the VA, only 136 DDIs (13.7%) were considered critical in all three systems. Our conclusion was that, overall, there is poor agreement among the compendia and the VA system.
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U2 - 10.1038/clpt.2009.198
DO - 10.1038/clpt.2009.198
M3 - Article
C2 - 19890252
AN - SCOPUS:72849125569
SN - 0009-9236
VL - 87
SP - 48
EP - 51
JO - Clinical Pharmacology and Therapeutics
JF - Clinical Pharmacology and Therapeutics
IS - 1
ER -