Comparison of bupivacaine, etidocaine, and saline for trigger-point therapy

S. R. Hameroff, B. Crago, D. Blitt, J. Womble, J. Kanel

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Injections of local anesthetics, saline, 'dry needling', or other stimuli at specific, tender loci (trigger or acupuncture points) are reportedly efficacious in treatment of chronic pain syndromes. In a randomized, double-blind crossover study, subjective responses of 15 patients with myofascial syndrome to trigger-point injections of either bupivacaine 0.5%, etiodocaine 1%, or physiologic saline without preservative were compared. Responses in six pain-related categories were determined before treatment and 15 minutes, 24 hours, and 7 days after treatment. Trigger-point injections with bupivacaine and etidocaine were generally preferred over saline in several pain-related categories. Implications and possible mechanisms are discussed.

Original languageEnglish (US)
Pages (from-to)752-755
Number of pages4
JournalUnknown Journal
Issue number10
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


Dive into the research topics of 'Comparison of bupivacaine, etidocaine, and saline for trigger-point therapy'. Together they form a unique fingerprint.

Cite this