TY - JOUR
T1 - Comparison of anterior chamber depth of normal and keratoconus eyes using scheimpflug photography
AU - Edmonds, Charles R.
AU - Wung, Shu Fen
AU - Pemberton, Bart
AU - Surrett, Steven
PY - 2009/5
Y1 - 2009/5
N2 - OBJECTIVES: To compare the corneal anterior chamber depth (ACD) adjusted by age and sex in normal and keratoconus eyes. METHODS: Scheimpflug photography with the Oculus Pentacam was used to measure the ACD of 162 normal and 41 keratoconus patients. RESULTS: Univariate analysis showed that the mean ACD of 162 normal subjects (3.18 ± 0.32 mm) was borderline significantly less than in 41 keratoconus patients (3.28 ± 0.40 mm; P=0.079). However, we found that sex (P=0.001) and age (P<0.001) are significantly related to ACD in all patients. Women with normal eyes had a significantly lower mean ACD (3.13 ± 0.34 mm) than men (3.27 ± 0.28 mm, P=0.008). Women with keratoconus eyes also had a lower mean ACD (3.16 ± 0.39 mm) than men with keratoconus (3.42 ± 0.36 mm, P=0.032). Bivariate regression showed that with each additional year of aging, the ACD was decreased by an average of 0.012 mm in a normal eye (P<0.001) and by 0.014 mm in a keratoconus eye (P<0.001). Regression analysis showed that sex (P=0.003), age (P<0.001), and keratoconus (P=0.003) are all significant variables for determining ACD. After adjusting for age and sex, keratoconus eyes had a significantly higher mean ACD (3.34 ± 0.34 mm) than normal eyes (3.18 ± 0.28 mm) (P=0.003). CONCLUSIONS: Sex, age, and keratoconus are all significant variables for ACD. After adjusting for age, keratoconus eyes of both genders had a significantly higher ACD than normal eyes of both genders. Women showed lower mean ACD than men in both normal and keratoconus eyes.
AB - OBJECTIVES: To compare the corneal anterior chamber depth (ACD) adjusted by age and sex in normal and keratoconus eyes. METHODS: Scheimpflug photography with the Oculus Pentacam was used to measure the ACD of 162 normal and 41 keratoconus patients. RESULTS: Univariate analysis showed that the mean ACD of 162 normal subjects (3.18 ± 0.32 mm) was borderline significantly less than in 41 keratoconus patients (3.28 ± 0.40 mm; P=0.079). However, we found that sex (P=0.001) and age (P<0.001) are significantly related to ACD in all patients. Women with normal eyes had a significantly lower mean ACD (3.13 ± 0.34 mm) than men (3.27 ± 0.28 mm, P=0.008). Women with keratoconus eyes also had a lower mean ACD (3.16 ± 0.39 mm) than men with keratoconus (3.42 ± 0.36 mm, P=0.032). Bivariate regression showed that with each additional year of aging, the ACD was decreased by an average of 0.012 mm in a normal eye (P<0.001) and by 0.014 mm in a keratoconus eye (P<0.001). Regression analysis showed that sex (P=0.003), age (P<0.001), and keratoconus (P=0.003) are all significant variables for determining ACD. After adjusting for age and sex, keratoconus eyes had a significantly higher mean ACD (3.34 ± 0.34 mm) than normal eyes (3.18 ± 0.28 mm) (P=0.003). CONCLUSIONS: Sex, age, and keratoconus are all significant variables for ACD. After adjusting for age, keratoconus eyes of both genders had a significantly higher ACD than normal eyes of both genders. Women showed lower mean ACD than men in both normal and keratoconus eyes.
KW - Anterior chamber depth
KW - Keratoconus
KW - Pentacam
KW - Scheimpflug photography
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U2 - 10.1097/ICL.0b013e31819cf5a6
DO - 10.1097/ICL.0b013e31819cf5a6
M3 - Article
C2 - 19421017
AN - SCOPUS:68549115593
SN - 1542-2321
VL - 35
SP - 120
EP - 122
JO - Eye and Contact Lens
JF - Eye and Contact Lens
IS - 3
ER -