Comparative aspects of coccidioidomycosis in animals and humans

Lisa F. Shubitz

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    50 Scopus citations

    Abstract

    Coccidioides spp. appear capable of infecting all mammals and at least some reptiles. Development of disease as a result of infection is species-dependent. Dogs seem to have a susceptibility similar to that of humans, with subclinical infections, mild-to-severe primary pulmonary disease, and disseminated disease. Whereas central nervous system disease in humans is typically meningitis, brain disease in dogs and cats takes the form of granulomatous parenchymal masses. Osteomyelitis is the most common form of disseminated disease in the dog, while skin lesions predominate in the cat. Orally administered azole antifungal agents are the backbone of therapy in animals as they are in humans.

    Original languageEnglish (US)
    Title of host publicationCoccidioidomycosis Sixth International Symposium
    PublisherBlackwell Publishing Inc.
    Pages395-403
    Number of pages9
    ISBN (Print)1573316881, 9781573316880
    DOIs
    StatePublished - Sep 2007

    Publication series

    NameAnnals of the New York Academy of Sciences
    Volume1111
    ISSN (Print)0077-8923
    ISSN (Electronic)1749-6632

    Keywords

    • Cats
    • Coccidioides
    • Coccidioidomycosis
    • Dogs
    • Horses
    • Llamas
    • Primates

    ASJC Scopus subject areas

    • Neuroscience(all)
    • Biochemistry, Genetics and Molecular Biology(all)
    • History and Philosophy of Science

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