Comorbidities play a larger role in predicting health-related quality of life compared to having an ostomy

Sushma Jain, Marcia L. McGory, Clifford Y. Ko, Alla Sverdlik, James S. Tomlinson, Christopher S. Wendel, Stephen Joel Coons, Susan M. Rawl, C. Max Schmidt, Marcia Grant, Ruth McCorkle, M. Jane Mohler, Carol M. Baldwin, Robert S Krouse

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Background: Previous research suggests an ostomy worsens health-related quality of life (HR-QOL), but comorbidities also can affect HR-QOL. Methods: Eligible patients had abdominal operation with ostomy (cases) or similar procedure without ostomy (controls). Patients were recruited for this case-control study from 3 Veterans Affairs hospital medical and pharmacy records. Comorbidities were assessed with Charlson-Deyo Comorbidity Index. Multinomial logistic regression evaluated the impact of comorbidities and having an ostomy on HR-QOL, measured using the Medical Outcomes Study Short Form 36 for Veterans. Results: A total of 237 ostomates (cases) and 268 controls were studied. Average age was 69 years; 64% of cases had colostomy, 36% ileostomy. Twenty-nine percent of patients had a high level of comorbidities. Cases and controls were similar except for reasons for undergoing surgery. High comorbidity was a significant predictor of low HR-QOL in 6 domains of the Short Form 36 for Veterans; having an ostomy was a significant predictor in 4. Conclusions: High comorbidity significantly influences low HR-QOL and impacted more domains than having an ostomy.

Original languageEnglish (US)
Pages (from-to)774-779
Number of pages6
JournalAmerican journal of surgery
Issue number6
StatePublished - Dec 2007


  • Comorbidites
  • Health-related quality of life
  • Ostomy

ASJC Scopus subject areas

  • Surgery


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