Combating SARS-CoV-2: leveraging microbicidal experiences with other emerging/re-emerging viruses

M. Khalid Ijaz, Syed A. Sattar, Joseph R. Rubino, Raymond W. Nims, Charles P. Gerba

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan City, China, late in December 2019 is an example of an emerging zoonotic virus that threatens public health and international travel and commerce. When such a virus emerges, there is often insufficient specific information available on mechanisms of virus dissemination from animal-to-human or from person-to-person, on the level or route of infection transmissibility or of viral release in body secretions/excretions, and on the survival of virus in aerosols or on surfaces. The effectiveness of available virucidal agents and hygiene practices as interventions for disrupting the spread of infection and the associated diseases may not be clear for the emerging virus. In the present review, we suggest that approaches for infection prevention and control (IPAC) for SARS-CoV-2 and future emerging/ re-emerging viruses can be invoked based on pre-existing data on microbicidal and hygiene effectiveness for related and unrelated enveloped viruses.

Original languageEnglish (US)
Article numbere9914
JournalPeerJ
Volume8
DOIs
StatePublished - 2020

Keywords

  • Ebola virus
  • Enterovirus D68
  • Hantaan virus
  • Lassa virus
  • MERS-CoV
  • Microbicides
  • Nipah virus
  • SARS-CoV
  • SARS-CoV-2
  • SFTSV

ASJC Scopus subject areas

  • General Neuroscience
  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences

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