Coccidioidomycosis: A diagnostic challenge

Lisa F. Shubitz, Sharon M. Dial

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations

    Abstract

    Coccidioidomycosis is a systemic fungal infection acquired endemically in the southwestern United States. Clinical disease is quite common in the dog; though less frequently recognized in the cat, disease is often severe at the time of diagnosis. Diagnosis can be a challenge because serology, while specific, is not very sensitive and quantitative titration of antibodies does not correlate entirely with clinical disease in dogs. Radiographs, serum biochemistry tests and complete blood counts are beneficial additions to the database when establishing a diagnosis; cytology, histopathology, and culture are definitive when available. Advanced imaging can detect central nervous system and subtle skeletal lesions. Disease can occur in most organs of the body and may prove a diagnostic challenge requiring several modalities. Coccidioidomycosis may need to be considered both in animals in the endemic region and in those with a travel history through it.

    Original languageEnglish (US)
    Pages (from-to)220-226
    Number of pages7
    JournalClinical Techniques in Small Animal Practice
    Volume20
    Issue number4
    DOIs
    StatePublished - Nov 2005

    Keywords

    • Cats
    • Coccidioides
    • Coccidioidomycosis
    • Computed tomography
    • Dogs
    • Endemic mycoses
    • Fungal diagnosis
    • Magnetic resonance imaging
    • Systemic mycoses

    ASJC Scopus subject areas

    • veterinary(all)

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