Co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system

D. K. Kang; M. J. Suter; C. Boudoux; P. S. Yachimski; W. P. Puricelli; N. S. Nishioka; M. Mino-Kenudson; G. Y. Lauwers; B. E. Bouma; G. J. Tearney

doi:10.1111/j.1365-2818.2010.03367.x

Co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system

D. K. Kang, M. J. Suter, C. Boudoux, P. S. Yachimski, W. P. Puricelli, N. S. Nishioka, M. Mino-Kenudson, G. Y. Lauwers, B. E. Bouma, G. J. Tearney

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Spectrally encoded confocal microscopy and optical frequency domain imaging are two non-contact optical imaging technologies that provide images of tissue cellular and architectural morphology, which are both used for histopathological diagnosis. Although spectrally encoded confocal microscopy has better transverse resolution than optical frequency domain imaging, optical frequency domain imaging can penetrate deeper into tissues, which potentially enables the visualization of different morphologic features. We have developed a co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system and have obtained preliminary images from human oesophageal biopsy samples to compare the capabilities of these imaging techniques for diagnosing oesophageal pathology.

Original language	English (US)
Pages (from-to)	87-91
Number of pages	5
Journal	Journal of Microscopy
Volume	239
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2818.2010.03367.x
State	Published - Aug 2010
Externally published	Yes

Keywords

Confocal microscopy
co-registered imaging
multi-modality imaging
optical coherence tomography

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

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10.1111/j.1365-2818.2010.03367.x

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title = "Co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system",

abstract = "Spectrally encoded confocal microscopy and optical frequency domain imaging are two non-contact optical imaging technologies that provide images of tissue cellular and architectural morphology, which are both used for histopathological diagnosis. Although spectrally encoded confocal microscopy has better transverse resolution than optical frequency domain imaging, optical frequency domain imaging can penetrate deeper into tissues, which potentially enables the visualization of different morphologic features. We have developed a co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system and have obtained preliminary images from human oesophageal biopsy samples to compare the capabilities of these imaging techniques for diagnosing oesophageal pathology.",

keywords = "Confocal microscopy, co-registered imaging, multi-modality imaging, optical coherence tomography",

author = "Kang, {D. K.} and Suter, {M. J.} and C. Boudoux and Yachimski, {P. S.} and Puricelli, {W. P.} and Nishioka, {N. S.} and M. Mino-Kenudson and Lauwers, {G. Y.} and Bouma, {B. E.} and Tearney, {G. J.}",

year = "2010",

month = aug,

doi = "10.1111/j.1365-2818.2010.03367.x",

language = "English (US)",

volume = "239",

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AU - Kang, D. K.

AU - Suter, M. J.

AU - Boudoux, C.

AU - Yachimski, P. S.

AU - Puricelli, W. P.

AU - Nishioka, N. S.

AU - Mino-Kenudson, M.

AU - Lauwers, G. Y.

AU - Bouma, B. E.

AU - Tearney, G. J.

PY - 2010/8

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AB - Spectrally encoded confocal microscopy and optical frequency domain imaging are two non-contact optical imaging technologies that provide images of tissue cellular and architectural morphology, which are both used for histopathological diagnosis. Although spectrally encoded confocal microscopy has better transverse resolution than optical frequency domain imaging, optical frequency domain imaging can penetrate deeper into tissues, which potentially enables the visualization of different morphologic features. We have developed a co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system and have obtained preliminary images from human oesophageal biopsy samples to compare the capabilities of these imaging techniques for diagnosing oesophageal pathology.

KW - Confocal microscopy

KW - co-registered imaging

KW - multi-modality imaging

KW - optical coherence tomography

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Co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system

Abstract

Keywords

ASJC Scopus subject areas

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