TY - JOUR
T1 - Clinical stage I endometrial carcinoma
T2 - Pitfalls in preoperative assessment with MR imaging: Work in progress
AU - Scoutt, Leslie M.
AU - McCarthy, Shirley M.
AU - Flynn, Stuart D
AU - Lange, Robert C.
AU - Long, Fred
AU - Smith, Robert C.
AU - Chambers, Setsuko K.
AU - Kohorn, Ernest
AU - Schwartz, Peter
AU - Chambers, Joseph T.
PY - 1995/2
Y1 - 1995/2
N2 - PURPOSE: To identify potential pitfalls in using magnetic resonance (MR) imaging to determine the depth of myometrial invasion in patients with clinical stage I endometrial carcinoma. MATERIALS AND METHODS: Forty women with clinical stage I endometrial carcinoma underwent preoperative pelvic MR imaging. Uterine length, tumor signal intensity, appearance of the junctional zone, presence of large polypoid tumors, leiomyomata, and congenital uterine anomalies were analyzed. Univariate logistic-regression analysis was performed to identify associations between incorrect MR staging and these variables. RESULTS: MR staging of IA, IB, and IC disease was 55% accurate (22 of 40 cases); MR differentiation of deep myometrial invasion (stage IC) from superficial disease (stages IA and IB) was 78% accurate (31 of 40 cases). Older age (P = .025), presence of polypoid tumors (P = .025), and difficulty in pathologic staging (P < .005) were significantly associated with incorrect MR assessment. CONCLUSION: When present, large polypoid tumors, leiomyomata, congenital anomalies, small uteri, and indistinct zonal anatomy may make it difficult to assess myometrial invasion at MR imaging.
AB - PURPOSE: To identify potential pitfalls in using magnetic resonance (MR) imaging to determine the depth of myometrial invasion in patients with clinical stage I endometrial carcinoma. MATERIALS AND METHODS: Forty women with clinical stage I endometrial carcinoma underwent preoperative pelvic MR imaging. Uterine length, tumor signal intensity, appearance of the junctional zone, presence of large polypoid tumors, leiomyomata, and congenital uterine anomalies were analyzed. Univariate logistic-regression analysis was performed to identify associations between incorrect MR staging and these variables. RESULTS: MR staging of IA, IB, and IC disease was 55% accurate (22 of 40 cases); MR differentiation of deep myometrial invasion (stage IC) from superficial disease (stages IA and IB) was 78% accurate (31 of 40 cases). Older age (P = .025), presence of polypoid tumors (P = .025), and difficulty in pathologic staging (P < .005) were significantly associated with incorrect MR assessment. CONCLUSION: When present, large polypoid tumors, leiomyomata, congenital anomalies, small uteri, and indistinct zonal anatomy may make it difficult to assess myometrial invasion at MR imaging.
KW - Uterine neoplasms, staging, 854.1214, 854.315, 854.324, 854.329
KW - Uterus, endometrium, 854.1214, 854.14782, 854.14789, 854.315
KW - Uterus, myometrium, 854.1214, 854.14782, 854.14789, 854.315
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U2 - 10.1148/radiology.194.2.7824739
DO - 10.1148/radiology.194.2.7824739
M3 - Article
C2 - 7824739
AN - SCOPUS:0028890886
SN - 0033-8419
VL - 194
SP - 567
EP - 572
JO - Radiology
JF - Radiology
IS - 2
ER -