Clinical determinants of aspirin resistance in diabetes

Hussein N. Yassine; Grace Davis-Gorman; Craig S. Stump; Stephen S. Thomson; Justin Peterson; Paul F. McDonagh

doi:10.1016/j.diabres.2010.07.008

Clinical determinants of aspirin resistance in diabetes

Hussein N. Yassine, Grace Davis-Gorman, Craig S. Stump, Stephen S. Thomson, Justin Peterson, Paul F. McDonagh

Medicine

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Recent studies indicate that not all diabetic subjects benefit from aspirin therapy. Our objective is to characterize diabetic subjects with aspirin resistance using urine thromboxane, and VerifyNow measures. Our results suggest that cardiovascular disease, microalbuminuria, poor diabetes control, and increased waist circumference help identify aspirin resistance in diabetes.

Original language	English (US)
Pages (from-to)	e19-e21
Journal	Diabetes Research and Clinical Practice
Volume	90
Issue number	1
DOIs	https://doi.org/10.1016/j.diabres.2010.07.008
State	Published - Oct 2010

Keywords

Aspirin Resistance
Diabetes
Insulin Resistance
Platelets
Thrombosis

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/j.diabres.2010.07.008

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title = "Clinical determinants of aspirin resistance in diabetes",

abstract = "Recent studies indicate that not all diabetic subjects benefit from aspirin therapy. Our objective is to characterize diabetic subjects with aspirin resistance using urine thromboxane, and VerifyNow measures. Our results suggest that cardiovascular disease, microalbuminuria, poor diabetes control, and increased waist circumference help identify aspirin resistance in diabetes.",

keywords = "Aspirin Resistance, Diabetes, Insulin Resistance, Platelets, Thrombosis",

author = "Yassine, {Hussein N.} and Grace Davis-Gorman and Stump, {Craig S.} and Thomson, {Stephen S.} and Justin Peterson and McDonagh, {Paul F.}",

note = "Funding Information: Supported by NIH HLB 58859 (P.F.M.), and State of Arizona TRIF Fund (C.S.S.) and Veteran Affairs Career Development Grant (C.S.S.). Funding Information: This study was supported, in part, by the Sarver Heart Center Hudson/Lovaas Endowment. We are indebted to Kirk Guyer and Corgenix staff for support with urine thromboxane kits, and Ji-eun Choi for her assistance in performing the ELISA assays.",

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AU - Yassine, Hussein N.

AU - Davis-Gorman, Grace

AU - Stump, Craig S.

AU - Thomson, Stephen S.

AU - Peterson, Justin

AU - McDonagh, Paul F.

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N2 - Recent studies indicate that not all diabetic subjects benefit from aspirin therapy. Our objective is to characterize diabetic subjects with aspirin resistance using urine thromboxane, and VerifyNow measures. Our results suggest that cardiovascular disease, microalbuminuria, poor diabetes control, and increased waist circumference help identify aspirin resistance in diabetes.

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KW - Diabetes

KW - Insulin Resistance

KW - Platelets

KW - Thrombosis

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Clinical determinants of aspirin resistance in diabetes

Abstract

Keywords

ASJC Scopus subject areas

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