CLEANING THE BRAIN THROUGH TURBULENT GLYMPHATIC FLOW: THE WASHING MACHINE HYPOTHESIS

Phillip H. Kuo

doi:10.2458/LYMPH.4787

CLEANING THE BRAIN THROUGH TURBULENT GLYMPHATIC FLOW: THE WASHING MACHINE HYPOTHESIS

Phillip H. Kuo

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In a thought experiment, a "washing machine" model is proposed based on turbulent flow from complex multi-dimensional forces to characterize fluid dynamics in the brain. The glymphatic system's hypothetical role in this system is illustrated in a series of diagrams. Implications of this model are discussed in terms of normal physiology and a variety of pathologic conditions such as brain atrophy and Alzheimer disease.

Original language	English (US)
Pages (from-to)	133-139
Number of pages	7
Journal	Lymphology
Volume	54
Issue number	3
DOIs	https://doi.org/10.2458/LYMPH.4787
State	Published - 2021

Keywords

"washing machine" model
Alzheimer disease
Brain a trophy
Cerebrospal fluid
Glymphatic system
Meningeal lymphatics
Turbulent flow

ASJC Scopus subject areas

Immunology and Allergy
Hematology

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10.2458/LYMPH.4787

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KW - Alzheimer disease

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KW - Meningeal lymphatics

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CLEANING THE BRAIN THROUGH TURBULENT GLYMPHATIC FLOW: THE WASHING MACHINE HYPOTHESIS

Abstract

Keywords

ASJC Scopus subject areas

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