Cigarette smoking and its possible effects on sperm

V. Kulikauskas, D. Blaustein, R. J. Ablin

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


The possible effects of cigarette smoking on sperm were evaluated by comparison of the quality of sperm from 103 smokers and 135 nonsmokers in a blind study. Smokers were found to possess significantly (P < 0.001) decreased density (number) and motility of their sperm than nonsmokers. Morphologic abnormalities, particularly bicephalia, although prevalent among individual smokers, did not differ significantly (P > 0.9) when a comparison of smokers versus nonsmokers was made as a whole. Based on these observations and those of others demonstrating the presence of mutagenic properties of smoke condensates, we suggest that decreases in sperm density and motility in cigarette smokers may be reflective of smoke condensate-induced mutagenic spermatogenital alterations.

Original languageEnglish (US)
Pages (from-to)526-528
Number of pages3
JournalFertility and Sterility
Issue number4
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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