Chromatin Modifications in Toxicology

James J. Galligan

doi:10.1021/acs.chemrestox.8b00267

Chromatin Modifications in Toxicology

James J. Galligan

Pharmacology and Toxicology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Histone modifications regulate chromatin structure and function. Primary and secondary metabolites stemming from environmental and chemical exposures may play a critical role in the underlying epigenomic state of a cell through covalent histone modifications. Future investigations should be focused on characterizing the "Histone Code" when performing toxicogenomic analyses.

Original language	English (US)
Pages (from-to)	794-795
Number of pages	2
Journal	Chemical Research in Toxicology
Volume	32
Issue number	5
DOIs	https://doi.org/10.1021/acs.chemrestox.8b00267
State	Published - May 20 2019

ASJC Scopus subject areas

Toxicology

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10.1021/acs.chemrestox.8b00267

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title = "Chromatin Modifications in Toxicology",

abstract = "Histone modifications regulate chromatin structure and function. Primary and secondary metabolites stemming from environmental and chemical exposures may play a critical role in the underlying epigenomic state of a cell through covalent histone modifications. Future investigations should be focused on characterizing the {"}Histone Code{"} when performing toxicogenomic analyses.",

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AU - Galligan, James J.

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AB - Histone modifications regulate chromatin structure and function. Primary and secondary metabolites stemming from environmental and chemical exposures may play a critical role in the underlying epigenomic state of a cell through covalent histone modifications. Future investigations should be focused on characterizing the "Histone Code" when performing toxicogenomic analyses.

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UR - https://www.scopus.com/pages/publications/85066093233#tab=citedBy

U2 - 10.1021/acs.chemrestox.8b00267

DO - 10.1021/acs.chemrestox.8b00267

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AN - SCOPUS:85066093233

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Chromatin Modifications in Toxicology

Abstract

ASJC Scopus subject areas

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