Chromatin Modifications in Toxicology

James J. Galligan

doi:10.1021/acs.chemrestox.8b00267

Chromatin Modifications in Toxicology

James J. Galligan

Pharmacology and Toxicology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Histone modifications regulate chromatin structure and function. Primary and secondary metabolites stemming from environmental and chemical exposures may play a critical role in the underlying epigenomic state of a cell through covalent histone modifications. Future investigations should be focused on characterizing the "Histone Code" when performing toxicogenomic analyses.

Original language	English (US)
Pages (from-to)	794-795
Number of pages	2
Journal	Chemical Research in Toxicology
Volume	32
Issue number	5
DOIs	https://doi.org/10.1021/acs.chemrestox.8b00267
State	Published - May 20 2019

ASJC Scopus subject areas

Toxicology

Access to Document

10.1021/acs.chemrestox.8b00267

Cite this

@article{c45576b8b6234060ae338abc0856fd1d,

title = "Chromatin Modifications in Toxicology",

abstract = "Histone modifications regulate chromatin structure and function. Primary and secondary metabolites stemming from environmental and chemical exposures may play a critical role in the underlying epigenomic state of a cell through covalent histone modifications. Future investigations should be focused on characterizing the {"}Histone Code{"} when performing toxicogenomic analyses.",

author = "Galligan, {James J.}",

note = "Publisher Copyright: {\textcopyright} 2018 American Chemical Society.",

year = "2019",

month = may,

day = "20",

doi = "10.1021/acs.chemrestox.8b00267",

language = "English (US)",

volume = "32",

pages = "794--795",

journal = "Chemical Research in Toxicology",

issn = "0893-228X",

publisher = "American Chemical Society",

number = "5",

}

TY - JOUR

T1 - Chromatin Modifications in Toxicology

AU - Galligan, James J.

PY - 2019/5/20

Y1 - 2019/5/20

N2 - Histone modifications regulate chromatin structure and function. Primary and secondary metabolites stemming from environmental and chemical exposures may play a critical role in the underlying epigenomic state of a cell through covalent histone modifications. Future investigations should be focused on characterizing the "Histone Code" when performing toxicogenomic analyses.

AB - Histone modifications regulate chromatin structure and function. Primary and secondary metabolites stemming from environmental and chemical exposures may play a critical role in the underlying epigenomic state of a cell through covalent histone modifications. Future investigations should be focused on characterizing the "Histone Code" when performing toxicogenomic analyses.

UR - http://www.scopus.com/inward/record.url?scp=85066093233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85066093233&partnerID=8YFLogxK

U2 - 10.1021/acs.chemrestox.8b00267

DO - 10.1021/acs.chemrestox.8b00267

M3 - Article

C2 - 30521321

AN - SCOPUS:85066093233

SN - 0893-228X

VL - 32

SP - 794

EP - 795

JO - Chemical Research in Toxicology

JF - Chemical Research in Toxicology

IS - 5

ER -

Chromatin Modifications in Toxicology

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this