Abstract
An organocatalytic enantioselective conjugate addition of cyclohexanones to maleimides has been developed. The process catalyzed by a (S)-pyrrolidine sulfonamide affords synthetically and medicinally useful chiral succinimides under mild reaction conditions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 473-476 |
| Number of pages | 4 |
| Journal | Synlett |
| Issue number | 4 |
| DOIs | |
| State | Published - 2011 |
| Externally published | Yes |
Keywords
- Michael reaction
- cyclic ketones
- maleimides
- pyrrolidine sulfonamide
ASJC Scopus subject areas
- Organic Chemistry
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