Abstract
An organocatalytic enantioselective conjugate addition of cyclohexanones to maleimides has been developed. The process catalyzed by a (S)-pyrrolidine sulfonamide affords synthetically and medicinally useful chiral succinimides under mild reaction conditions.
Original language | English (US) |
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Pages (from-to) | 473-476 |
Number of pages | 4 |
Journal | Synlett |
Issue number | 4 |
DOIs | |
State | Published - 2011 |
Externally published | Yes |
Keywords
- Michael reaction
- cyclic ketones
- maleimides
- pyrrolidine sulfonamide
ASJC Scopus subject areas
- Organic Chemistry