Abstract
22 patients with localised (stage I or II) diffuse lymphoma were treated with chemotherapy at the time of diagnosis. 14 patients received chemotherapy as the only treatment, and 8 received chemotherapy plus local irradiation. Doxorubicin-containing drug regimens were used in 20 patients. All 22 patients achieved a complete remission and remain alive with a median survival from the time of diagnosis of 27+ months. 21 patients (95%) have remained continuously free of disease with a median disease-free survival from the completion of chemotherapy of 23+ months. These findings provide a strong rationale for further clinical trials of chemotherapy alone or chemotherapy followed by regional radiotherapy for localised stages of diffuse lymphoma.
Original language | English (US) |
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Pages (from-to) | 358-360 |
Number of pages | 3 |
Journal | The Lancet |
Volume | 313 |
Issue number | 8112 |
DOIs | |
State | Published - Feb 17 1979 |
ASJC Scopus subject areas
- General Medicine