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Chemistry and pharmacology of imexon and related cyanoaziridines
W. A. Remers, R. T. Dorr
Cancer Center
Research output
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Contribution to journal
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Article
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peer-review
8
Scopus citations
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Medicine & Life Sciences
4-imino-1,3-diazabicyclo(3.1.0)hexan-2-one
100%
Pharmacology
32%
gemcitabine
27%
Sulfhydryl Compounds
17%
ciamexon
17%
azimexon
16%
Aziridines
16%
Cell Culture Techniques
12%
Cyclization
12%
Cultured Tumor Cells
11%
Alkylation
10%
Clinical Trials
10%
Freeze Drying
10%
Phase II Clinical Trials
10%
hydroxide ion
9%
Chromatography
8%
Multiple Myeloma
8%
Antineoplastic Agents
7%
Pancreatic Neoplasms
7%
Non-Hodgkin's Lymphoma
7%
Cysteine
7%
Reactive Oxygen Species
6%
Water
5%
Neoplasms
5%
DNA
4%
Pharmaceutical Preparations
3%
Chemical Compounds
Gemcitabine
74%
Immunomodulating Agent
28%
Chemistry
28%
Thiol
27%
Aziridines
20%
Reactive Oxygen Metabolite
15%
Antineoplastic Agent
14%
Cysteine
14%
Hydroxide
13%
Enantiomer
12%
Water Soluble
12%
Cyclization Reaction
12%
Drug
8%
Ion
6%