Charting the future frontier(S) of particle production

This short note describes the long collaborative effort between Arizona and Kraków, showing some of the key strangeness signatures of quark-gluon plasma. It further presents an annotated catalog of foundational questions defining the research frontiers which I believe can be addressed in the foreseeable future in the context of relativistic heavy-ion collision experiments. The list includes topics that are specific to the field, and ventures towards the known-to-be-unknown that may have a better chance with ions as compared to elementary interactions.