Characterizing causality in cancer

Elena Rondeau, Thomas Pradeu, Andreas Bikfalvi, Nicolas Larmonier

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Philosophers have explored the concept of causality for centuries. Here we argue that ideas about causality from philosophy can help scientists to better understand how cancerous tumors grow and spread in the body. After outlining six characteristics of causality that are relevant to cancer, we emphasize the importance of feedback loops and interactions between tumor-cell-intrinsic and tumor-cell-extrinsic factors for explaining the formation and dissemination of tumors.

Original languageEnglish (US)
Article numbere53755
StatePublished - Nov 2019

ASJC Scopus subject areas

  • General Neuroscience
  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology

Cite this