Characterization of products of excimer laser ablation of collagen

Marwood N. Ediger; David W. Hahn; George H. Pettit

doi:10.1117/12.209832

Characterization of products of excimer laser ablation of collagen

Marwood N. Ediger, David W. Hahn, George H. Pettit

Research output: Contribution to journal › Conference article › peer-review

2 Scopus citations

Abstract

The presence of hydroxyl radicals in ArF excimer ablation sites in bovine corneal tissue has been investigated by laser-induced fluorescence and Raman spectroscopy. Raman spectroscopy has also been applied to examine the time-resolved temperature of the water component of the ablation site as well as the spatially selective measurement of surface desiccation. Results indicate that the hydroxyl radical is not generate in abundance during the ablation process. Also, Raman monitoring of the ablation site demonstrates no detectable heating during ArF irradiation, while elevated temperatures are observed following exposure of the corneal surface to a Er:YAG laser. Finally, comparison of C-H and O-H Raman bands shows potential utility as a spatially selective means for monitoring tissue hydration.

Original language	English (US)
Pages (from-to)	106-110
Number of pages	5
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	2393
DOIs	https://doi.org/10.1117/12.209832
State	Published - May 22 1995
Externally published	Yes
Event	Ophthalmic Technologies V 1995 - San Jose, United States Duration: Feb 1 1995 → Feb 28 1995

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.209832

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title = "Characterization of products of excimer laser ablation of collagen",

abstract = "The presence of hydroxyl radicals in ArF excimer ablation sites in bovine corneal tissue has been investigated by laser-induced fluorescence and Raman spectroscopy. Raman spectroscopy has also been applied to examine the time-resolved temperature of the water component of the ablation site as well as the spatially selective measurement of surface desiccation. Results indicate that the hydroxyl radical is not generate in abundance during the ablation process. Also, Raman monitoring of the ablation site demonstrates no detectable heating during ArF irradiation, while elevated temperatures are observed following exposure of the corneal surface to a Er:YAG laser. Finally, comparison of C-H and O-H Raman bands shows potential utility as a spatially selective means for monitoring tissue hydration.",

author = "Ediger, {Marwood N.} and Hahn, {David W.} and Pettit, {George H.}",

year = "1995",

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doi = "10.1117/12.209832",

language = "English (US)",

volume = "2393",

pages = "106--110",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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TY - JOUR

T1 - Characterization of products of excimer laser ablation of collagen

AU - Ediger, Marwood N.

AU - Hahn, David W.

AU - Pettit, George H.

PY - 1995/5/22

Y1 - 1995/5/22

N2 - The presence of hydroxyl radicals in ArF excimer ablation sites in bovine corneal tissue has been investigated by laser-induced fluorescence and Raman spectroscopy. Raman spectroscopy has also been applied to examine the time-resolved temperature of the water component of the ablation site as well as the spatially selective measurement of surface desiccation. Results indicate that the hydroxyl radical is not generate in abundance during the ablation process. Also, Raman monitoring of the ablation site demonstrates no detectable heating during ArF irradiation, while elevated temperatures are observed following exposure of the corneal surface to a Er:YAG laser. Finally, comparison of C-H and O-H Raman bands shows potential utility as a spatially selective means for monitoring tissue hydration.

AB - The presence of hydroxyl radicals in ArF excimer ablation sites in bovine corneal tissue has been investigated by laser-induced fluorescence and Raman spectroscopy. Raman spectroscopy has also been applied to examine the time-resolved temperature of the water component of the ablation site as well as the spatially selective measurement of surface desiccation. Results indicate that the hydroxyl radical is not generate in abundance during the ablation process. Also, Raman monitoring of the ablation site demonstrates no detectable heating during ArF irradiation, while elevated temperatures are observed following exposure of the corneal surface to a Er:YAG laser. Finally, comparison of C-H and O-H Raman bands shows potential utility as a spatially selective means for monitoring tissue hydration.

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U2 - 10.1117/12.209832

DO - 10.1117/12.209832

M3 - Conference article

AN - SCOPUS:33847417597

SN - 0277-786X

VL - 2393

SP - 106

EP - 110

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Ophthalmic Technologies V 1995

Y2 - 1 February 1995 through 28 February 1995

ER -

Characterization of products of excimer laser ablation of collagen

Abstract

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