TY - JOUR
T1 - Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA
AU - Campo, M.
AU - Shrestha, A.
AU - Oren, E.
AU - Thiede, H.
AU - Duchin, J.
AU - Narita, M.
AU - Crothers, K.
PY - 2014/7
Y1 - 2014/7
N2 - The impact of hepatitis C virus infection (HCI), the most common bloodborne virus infection in the USA, on outcome of active tuberculosis (TB) treatment is largely unknown. We aimed to describe characteristics of TB patients with hepatitis C virus infection (TB-HCI) in King County, Washington, including TB treatment duration and outcome. We reviewed 1510 records of patients treated for active TB at the Public Health - Seattle & King County Tuberculosis Control Program between 2000 and 2010, and identified 53 with HCI. Advanced age, being born in the USA, HIV infection, homelessness and injection drug use were independently associated with HCI in TB cases. Independent factors associated with increased treatment duration included HIV infection, excess alcohol use, extrapulmonary TB, and any drug-resistant TB disease. Our findings suggest that TB-HCI patients can be successfully treated for active TB without extending treatment duration.
AB - The impact of hepatitis C virus infection (HCI), the most common bloodborne virus infection in the USA, on outcome of active tuberculosis (TB) treatment is largely unknown. We aimed to describe characteristics of TB patients with hepatitis C virus infection (TB-HCI) in King County, Washington, including TB treatment duration and outcome. We reviewed 1510 records of patients treated for active TB at the Public Health - Seattle & King County Tuberculosis Control Program between 2000 and 2010, and identified 53 with HCI. Advanced age, being born in the USA, HIV infection, homelessness and injection drug use were independently associated with HCI in TB cases. Independent factors associated with increased treatment duration included HIV infection, excess alcohol use, extrapulmonary TB, and any drug-resistant TB disease. Our findings suggest that TB-HCI patients can be successfully treated for active TB without extending treatment duration.
KW - Hepatitis C
KW - tuberculosis (TB)
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U2 - 10.1017/S0950268813002355
DO - 10.1017/S0950268813002355
M3 - Article
C2 - 24067406
AN - SCOPUS:84901464188
SN - 0950-2688
VL - 142
SP - 1459
EP - 1466
JO - Epidemiology and infection
JF - Epidemiology and infection
IS - 7
ER -