Characterization of cellular sequences flanking an integrated bovine leukemia virus genome

E. P. Gelmann, A. Burny, R. Kettmann

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We cloned a 20.2-kilobase fragment, including the unique proviral integration site, from the tumor tissue DNA of a bovine leukemia virus-induced lymphoma (tumor 1351). This clone contained 5.5 kilobases of flanking sequences at either side of the full-length integrated viral genome. Hybridization analysis of both 3' and 5' cellular flanking regions provided no evidence for rearrangements at this locus in other tumors, RNA transcription from either flanking region, or homology to eight known onc genes.

Original languageEnglish (US)
Pages (from-to)988-990
Number of pages3
JournalJournal of virology
Volume52
Issue number3
DOIs
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Fingerprint

Dive into the research topics of 'Characterization of cellular sequences flanking an integrated bovine leukemia virus genome'. Together they form a unique fingerprint.

Cite this