TY - JOUR
T1 - Changes in physical activity, sedentary time, and risk of falling
T2 - The Women's Health Initiative Observational Study
AU - Bea, Jennifer W.
AU - Thomson, Cynthia A.
AU - Wallace, Robert B.
AU - Wu, Chunyuan
AU - Seguin, Rebecca A.
AU - Going, Scott B.
AU - LaCroix, Andrea
AU - Eaton, Charles
AU - Ockene, Judith K.
AU - LaMonte, Michael J.
AU - Jackson, Rebecca
AU - Jerry Mysiw, W.
AU - Wactawski-Wende, Jean
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Falling significantly affects quality of life, morbidity, and mortality among older adults. We sought to evaluate the prospective association between sedentary time, physical activity, and falling among post-menopausal women aged 50–79 years recruited to the Women's Health Initiative Observational Study between 1993 and 1998 from 40 clinical centers across the United States. Baseline (B) and change in each of the following were evaluated at year 3 (Y3) and year 6 (Y6; baseline n = 93,676; Y3 n = 76,598; Y6 n = 75,428): recreational physical activity (MET-h/wk), sitting, sleeping (min/day), and lean body mass by dual energy X-ray absorptiometry (subset N = 6475). Falls per year (0, 1, 2, ≥ 3) were assessed annually by self-report questionnaire and then dichotomized as ≤ 1 and ≥ 2 falls/year. Logistic regression models were adjusted for demographics, body mass index, fall history, tobacco and alcohol use, medical conditions, and medications. Higher baseline activity was associated with greater risk of falling at Y6 (18%; p for trend < 0.0001). Increasing sedentary time minimally decreased falling (1% Y3; 2% Y6; p < 0.05). Increasing activity up to ≥ 9 MET-h/wk. (OR: 1.12, 95% CI: 1.03–1.22) or maintaining ≥ 9 MET-h/wk. (OR: 1.20, 95% CI: 1.13–1.29) increased falling at Y3 and Y6 (p for trend < 0.001). Adding lean body mass to the models attenuated these relationships. Physically active lifestyles increased falling among post-menopausal women. Additional fall prevention strategies, such as balance and resistance training, should be evaluated to assist post-menopausal women in reaching or maintaining levels of aerobic activity known to prevent and manage several chronic diseases.
AB - Falling significantly affects quality of life, morbidity, and mortality among older adults. We sought to evaluate the prospective association between sedentary time, physical activity, and falling among post-menopausal women aged 50–79 years recruited to the Women's Health Initiative Observational Study between 1993 and 1998 from 40 clinical centers across the United States. Baseline (B) and change in each of the following were evaluated at year 3 (Y3) and year 6 (Y6; baseline n = 93,676; Y3 n = 76,598; Y6 n = 75,428): recreational physical activity (MET-h/wk), sitting, sleeping (min/day), and lean body mass by dual energy X-ray absorptiometry (subset N = 6475). Falls per year (0, 1, 2, ≥ 3) were assessed annually by self-report questionnaire and then dichotomized as ≤ 1 and ≥ 2 falls/year. Logistic regression models were adjusted for demographics, body mass index, fall history, tobacco and alcohol use, medical conditions, and medications. Higher baseline activity was associated with greater risk of falling at Y6 (18%; p for trend < 0.0001). Increasing sedentary time minimally decreased falling (1% Y3; 2% Y6; p < 0.05). Increasing activity up to ≥ 9 MET-h/wk. (OR: 1.12, 95% CI: 1.03–1.22) or maintaining ≥ 9 MET-h/wk. (OR: 1.20, 95% CI: 1.13–1.29) increased falling at Y3 and Y6 (p for trend < 0.001). Adding lean body mass to the models attenuated these relationships. Physically active lifestyles increased falling among post-menopausal women. Additional fall prevention strategies, such as balance and resistance training, should be evaluated to assist post-menopausal women in reaching or maintaining levels of aerobic activity known to prevent and manage several chronic diseases.
KW - Accidental falls
KW - Exercise
KW - Falls
KW - Menopause
KW - Sedentary lifestyle
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U2 - 10.1016/j.ypmed.2016.11.025
DO - 10.1016/j.ypmed.2016.11.025
M3 - Article
C2 - 27932054
AN - SCOPUS:85007108703
SN - 0091-7435
VL - 95
SP - 103
EP - 109
JO - Preventive Medicine
JF - Preventive Medicine
ER -