TY - JOUR
T1 - Challenges and opportunities for the prevention and treatment of cardiovascular disease among young adults
T2 - Report from a national heart, lung, and blood institute working group
AU - Gooding, Holly C.
AU - Gidding, Samuel S.
AU - Moran, Andrew E.
AU - Redmond, Nicole
AU - Allen, Norrina B.
AU - Bacha, Fida
AU - Burns, Trudy L.
AU - Catov, Janet M.
AU - Grandner, Michael A.
AU - Harris, Kathleen Mullan
AU - Johnson, Heather M.
AU - Kiernan, Michaela
AU - Lewis, Tené T.
AU - Matthews, Karen A.
AU - Monaghan, Maureen
AU - Robinson, Jennifer G.
AU - Tate, Deborah
AU - Bibbins-Domingo, Kirsten
AU - Spring, Bonnie
N1 - Funding Information:
This work was supported by the National Heart, Lung, and Blood Institute (NHLBI) with a contribution from the Office of Behavioral and Social Sciences Research. Dr Allen was supported by NHLBI grants R01HL14866, R01HL136942, and R01HL133860; NHLBI contract HHSN268201800003I; and American Heart Association (AHA) grants 17SFRN33660752 and 18SRG343600001. Dr Bacha is supported by the US Department of Agriculture’s Agricultural Research Service Current Research Information System Award 3092-5-001-057. Dr Burns was supported by NHLBI grant R01HL121230. Dr Catov was supported by AHA grants 16SFRN28930000, 19SCG34940002, and 18SCG34350001; and NHLBI grant R21HL145419. Dr Gooding was supported by an NHLBI career development award (K23HL122361). Dr Grandner was supported by research grants from Kemin Foods, Nexalin Technology, Jazz Pharmaceuticals, and the National Institute of Minority Health and Health Disparities R01MD011600. Dr Harris was supported by Eunice Kennedy Shriver National Institute of Child Health and Human Development grant P01HD031921 for the National Longitudinal Study of Adolescent to Adult Health (Add Health). Dr Johnson was supported by NHLBI grant R01HL132148. Dr Kiernan was supported by NHLBI research grant R01HL128666. Dr Lewis was supported by NHLBI grant R01HL130471. Dr Monaghan was supported by an American Diabetes Association Pathway to Stop Diabetes Accelerator Award #1-18-ACE-27. Dr Moran was supported by an NHLBI research grant R01HL107475. Dr Robinson was funded by research grants to her institution from Acasti, Amarin, Amgen, Astra-Zeneca, Eli Lilly, Esperion, Medicines Company, Merck, Novartis, Novo-Nordisk, Regeneron, and Sanofi. Dr Spring was supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) research grants R01DK108678 and R01DK097364 and AHA grant 14SFRN20740001. Dr Tate was supported by research grants from the NHLBI (R01HL122144, R01HL127341) and NIDDK (R01DK103668, R01DK095078). The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the NHLBI, the National Institutes of Health, or the US Department of Health and Human Services.
Publisher Copyright:
© 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.
PY - 2020/10/6
Y1 - 2020/10/6
N2 - Improvements in cardiovascular disease (CVD) rates among young adults in the past 2 decades have been offset by increasing racial/ethnic and gender disparities, persistence of unhealthy lifestyle habits, overweight and obesity, and other CVD risk factors. To enhance the promotion of cardiovascular health among young adults 18 to 39 years old, the medical and broader public health community must understand the biological, interpersonal, and behavioral features of this life stage. Therefore, the National Heart, Lung, and Blood Institute, with support from the Office of Behavioral and Social Science Research, convened a 2-day workshop in Bethesda, Maryland, in September 2017 to identify research challenges and opportunities related to the cardiovascular health of young adults. The current generation of young adults live in an environment undergoing substantial economic, social, and technological transformations, differentiating them from prior research cohorts of young adults. Although the accumulation of clinical and behavioral risk factors for CVD begins early in life, and research suggests early risk is an important determinant of future events, few trials have studied prevention and treatment of CVD in participants <40 years old. Building an evidence base for CVD prevention in this population will require the engagement of young adults, who are often disconnected from the healthcare system and may not prioritize long-term health. These changes demand a repositioning of existing evidence-based treatments to accommodate new sociotechnical contexts. In this article, the authors review the recent literature and current research opportunities to advance the cardiovascular health of today’s young adults.
AB - Improvements in cardiovascular disease (CVD) rates among young adults in the past 2 decades have been offset by increasing racial/ethnic and gender disparities, persistence of unhealthy lifestyle habits, overweight and obesity, and other CVD risk factors. To enhance the promotion of cardiovascular health among young adults 18 to 39 years old, the medical and broader public health community must understand the biological, interpersonal, and behavioral features of this life stage. Therefore, the National Heart, Lung, and Blood Institute, with support from the Office of Behavioral and Social Science Research, convened a 2-day workshop in Bethesda, Maryland, in September 2017 to identify research challenges and opportunities related to the cardiovascular health of young adults. The current generation of young adults live in an environment undergoing substantial economic, social, and technological transformations, differentiating them from prior research cohorts of young adults. Although the accumulation of clinical and behavioral risk factors for CVD begins early in life, and research suggests early risk is an important determinant of future events, few trials have studied prevention and treatment of CVD in participants <40 years old. Building an evidence base for CVD prevention in this population will require the engagement of young adults, who are often disconnected from the healthcare system and may not prioritize long-term health. These changes demand a repositioning of existing evidence-based treatments to accommodate new sociotechnical contexts. In this article, the authors review the recent literature and current research opportunities to advance the cardiovascular health of today’s young adults.
KW - Cardiovascular disease prevention
KW - Cardiovascular disease risk factors
KW - Primary prevention
KW - Young adults
UR - http://www.scopus.com/inward/record.url?scp=85092681812&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85092681812&partnerID=8YFLogxK
U2 - 10.1161/JAHA.120.016115
DO - 10.1161/JAHA.120.016115
M3 - Review article
C2 - 32993438
AN - SCOPUS:85092681812
VL - 9
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
SN - 2047-9980
IS - 19
M1 - e016115
ER -