Cerebellar atrophy: Relationship to aging and cerebral atrophy

William C. Koller, Sander L. Glatt, Jacob H. Fox, Alfred W. Kaszniak, Robert S. Wilson, Michael S. Huckman

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


We studied the incidence of computed tomography evidence of cerebellar atrophy in 20 elderly patients with dementia, 20 age-matched controls, and 40 younger normal subjects. Cerebellar vermian atrophy was present in 6 of 20 demented patients, 7 of 20 elderly controls, and 1 of 40 younger controls. There was no other atrophy of infratentorial structures except for occasional enlargement of the cisterna magna and cerebellopontine angle cisterns. Vermian atrophy did not correlate with cerebral atrophy (enlargement of either lateral ventricles or cortical sulci). None of these patients had clinical signs of cerebellar dysfunction. Therefore, atrophy of the cerebellar vermis may occur selectively with aging, without atrophy of the cerebral cortex, and without clinical manifestations.

Original languageEnglish (US)
Pages (from-to)1486-1488
Number of pages3
Issue number11
StatePublished - Nov 1981

ASJC Scopus subject areas

  • Clinical Neurology


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