Cell surface turnover and shedding of fucosyl-glycoprotein in L6 cells

Thomas C. Doetschman

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The disappearance of electrophoretically identifiable 3H-fucosylated glycoproteins from the cell surface of L6 cells is random and follows monophasic kinetics with a half-life of 9 hours. Approximately 47% and 53% of that loss is due to shedding and to degradation, respectively. Shedding also occurs with monophasic kinetics. Most of the electrophoretically identifiable-shed fucosyl-glycoproteins are released with homogeneous rates but do not represent a random sampling of the surface.

Original languageEnglish (US)
Pages (from-to)379-390
Number of pages12
JournalCell Biology International Reports
Issue number4
StatePublished - Apr 1980

ASJC Scopus subject areas

  • Cell Biology


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