Celiac Sprue in Down's Syndrome: Considerations on a Pathogenetic Link

Thomas V. Nowak; Fayez K. Ghishan; Konrad Schulze‐Delrieu

doi:10.1111/j.1572-0241.1983.tb01871.x

Celiac Sprue in Down's Syndrome: Considerations on a Pathogenetic Link

Thomas V. Nowak
, Fayez K. Ghishan
, Konrad Schulze‐Delrieu

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The association of celiac disease with Down's syndrome is described in two patients who presented with features of the malabsorption syndrome. The diagnosis was readily made by peroral jejunal mucosal biopsy. Both patients responded clinically to dietary gluten withdrawal and one patient demonstrated a recrudescence of symptoms and reappearance of jejunal mucosal atrophy upon rechallenge with dietary gluten. Genetic considerations in the etiology of both disorders are discussed.

Original language	English (US)
Pages (from-to)	280-283
Number of pages	4
Journal	The American Journal of Gastroenterology
Volume	78
Issue number	5
DOIs	https://doi.org/10.1111/j.1572-0241.1983.tb01871.x
State	Published - May 1983
Externally published	Yes

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.1111/j.1572-0241.1983.tb01871.x

Cite this

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abstract = "The association of celiac disease with Down's syndrome is described in two patients who presented with features of the malabsorption syndrome. The diagnosis was readily made by peroral jejunal mucosal biopsy. Both patients responded clinically to dietary gluten withdrawal and one patient demonstrated a recrudescence of symptoms and reappearance of jejunal mucosal atrophy upon rechallenge with dietary gluten. Genetic considerations in the etiology of both disorders are discussed.",

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AB - The association of celiac disease with Down's syndrome is described in two patients who presented with features of the malabsorption syndrome. The diagnosis was readily made by peroral jejunal mucosal biopsy. Both patients responded clinically to dietary gluten withdrawal and one patient demonstrated a recrudescence of symptoms and reappearance of jejunal mucosal atrophy upon rechallenge with dietary gluten. Genetic considerations in the etiology of both disorders are discussed.

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Celiac Sprue in Down's Syndrome: Considerations on a Pathogenetic Link

Abstract

ASJC Scopus subject areas

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