TY - JOUR
T1 - Celiac Sprue in Down's Syndrome
T2 - Considerations on a Pathogenetic Link
AU - Nowak, Thomas V.
AU - Ghishan, Fayez K.
AU - Schulze‐Delrieu, Konrad
PY - 1983/5
Y1 - 1983/5
N2 - The association of celiac disease with Down's syndrome is described in two patients who presented with features of the malabsorption syndrome. The diagnosis was readily made by peroral jejunal mucosal biopsy. Both patients responded clinically to dietary gluten withdrawal and one patient demonstrated a recrudescence of symptoms and reappearance of jejunal mucosal atrophy upon rechallenge with dietary gluten. Genetic considerations in the etiology of both disorders are discussed.
AB - The association of celiac disease with Down's syndrome is described in two patients who presented with features of the malabsorption syndrome. The diagnosis was readily made by peroral jejunal mucosal biopsy. Both patients responded clinically to dietary gluten withdrawal and one patient demonstrated a recrudescence of symptoms and reappearance of jejunal mucosal atrophy upon rechallenge with dietary gluten. Genetic considerations in the etiology of both disorders are discussed.
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U2 - 10.1111/j.1572-0241.1983.tb01871.x
DO - 10.1111/j.1572-0241.1983.tb01871.x
M3 - Article
C2 - 6221657
AN - SCOPUS:0020632208
VL - 78
SP - 280
EP - 283
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
SN - 0002-9270
IS - 5
ER -