CD44 Variant isoforms in head and neck squamous cell carcinoma progression

Steven J. Wang, Gabriel Wong, Anne Martine De Heer, Weiliang Xia, Lilly Y.W. Bourguignon

Research output: Contribution to journalArticlepeer-review

133 Scopus citations

Abstract

Objectives/Hypothesis: The CD44 family of receptors includes multiple variant isoforms, several of which have been linked to malignant properties including migration, invasion, and metastasis. The objective of this study was to investigate the role of the CD44 v3, v6, and v10 variant isoforms in head and neck squamous cell carcinoma (HNSCC) tumor progression behaviors. Study Design.

Original languageEnglish (US)
Pages (from-to)1518-1530
Number of pages13
JournalLaryngoscope
Volume119
Issue number8
DOIs
StatePublished - Aug 2009
Externally publishedYes

Keywords

  • CD44
  • Head and neck squamous cell carcinoma
  • Hyaluronan

ASJC Scopus subject areas

  • Otorhinolaryngology

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