CD44 Variant isoforms in head and neck squamous cell carcinoma progression

Steven J. Wang; Gabriel Wong; Anne Martine De Heer; Weiliang Xia; Lilly Y.W. Bourguignon

doi:10.1002/lary.20506

CD44 Variant isoforms in head and neck squamous cell carcinoma progression

Steven J. Wang, Gabriel Wong, Anne Martine De Heer, Weiliang Xia, Lilly Y.W. Bourguignon

Research output: Contribution to journal › Article › peer-review

151 Scopus citations

Abstract

Objectives/Hypothesis: The CD44 family of receptors includes multiple variant isoforms, several of which have been linked to malignant properties including migration, invasion, and metastasis. The objective of this study was to investigate the role of the CD44 v3, v6, and v10 variant isoforms in head and neck squamous cell carcinoma (HNSCC) tumor progression behaviors. Study Design.

Original language	English (US)
Pages (from-to)	1518-1530
Number of pages	13
Journal	Laryngoscope
Volume	119
Issue number	8
DOIs	https://doi.org/10.1002/lary.20506
State	Published - Aug 2009
Externally published	Yes

Keywords

CD44
Head and neck squamous cell carcinoma
Hyaluronan

ASJC Scopus subject areas

Otorhinolaryngology

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10.1002/lary.20506

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abstract = "Objectives/Hypothesis: The CD44 family of receptors includes multiple variant isoforms, several of which have been linked to malignant properties including migration, invasion, and metastasis. The objective of this study was to investigate the role of the CD44 v3, v6, and v10 variant isoforms in head and neck squamous cell carcinoma (HNSCC) tumor progression behaviors. Study Design.",

keywords = "CD44, Head and neck squamous cell carcinoma, Hyaluronan",

author = "Wang, {Steven J.} and Gabriel Wong and {De Heer}, {Anne Martine} and Weiliang Xia and Bourguignon, {Lilly Y.W.}",

year = "2009",

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AU - Wang, Steven J.

AU - Wong, Gabriel

AU - De Heer, Anne Martine

AU - Xia, Weiliang

AU - Bourguignon, Lilly Y.W.

PY - 2009/8

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AB - Objectives/Hypothesis: The CD44 family of receptors includes multiple variant isoforms, several of which have been linked to malignant properties including migration, invasion, and metastasis. The objective of this study was to investigate the role of the CD44 v3, v6, and v10 variant isoforms in head and neck squamous cell carcinoma (HNSCC) tumor progression behaviors. Study Design.

KW - CD44

KW - Head and neck squamous cell carcinoma

KW - Hyaluronan

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CD44 Variant isoforms in head and neck squamous cell carcinoma progression

Abstract

Keywords

ASJC Scopus subject areas

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