CD44 in Bladder Cancer

Jason Duex; Dan Theodorescu

doi:10.3390/cancers16061195

CD44 in Bladder Cancer

Jason Duex
, Dan Theodorescu

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

The glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These same facts make CD44 a strong therapeutic target in many cancer types, including bladder cancer.

Original language	English (US)
Article number	1195
Journal	Cancers
Volume	16
Issue number	6
DOIs	https://doi.org/10.3390/cancers16061195
State	Published - Mar 2024
Externally published	Yes

Keywords

androgen receptor
bladder cancer
CD44
glycosylation
hyaluronic acid

ASJC Scopus subject areas

Oncology
Cancer Research

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10.3390/cancers16061195

Cite this

@article{78c0907f9b6b439880ec30741389b615,

title = "CD44 in Bladder Cancer",

abstract = "The glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These same facts make CD44 a strong therapeutic target in many cancer types, including bladder cancer.",

keywords = "androgen receptor, bladder cancer, CD44, glycosylation, hyaluronic acid",

author = "Jason Duex and Dan Theodorescu",

note = "Publisher Copyright: {\textcopyright} 2024 by the authors.",

year = "2024",

month = mar,

doi = "10.3390/cancers16061195",

language = "English (US)",

volume = "16",

journal = "Cancers",

issn = "2072-6694",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "6",

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TY - JOUR

T1 - CD44 in Bladder Cancer

AU - Duex, Jason

AU - Theodorescu, Dan

PY - 2024/3

Y1 - 2024/3

N2 - The glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These same facts make CD44 a strong therapeutic target in many cancer types, including bladder cancer.

AB - The glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These same facts make CD44 a strong therapeutic target in many cancer types, including bladder cancer.

KW - androgen receptor

KW - bladder cancer

KW - CD44

KW - glycosylation

KW - hyaluronic acid

UR - https://www.scopus.com/pages/publications/85188745918

UR - https://www.scopus.com/pages/publications/85188745918#tab=citedBy

U2 - 10.3390/cancers16061195

DO - 10.3390/cancers16061195

M3 - Review article

AN - SCOPUS:85188745918

SN - 2072-6694

VL - 16

JO - Cancers

JF - Cancers

IS - 6

M1 - 1195

ER -

CD44 in Bladder Cancer

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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