Causes of Death in Acute Leukemia: A Ten-Year Study of 414 Patients From 1954-1963

Evan M. Hersh; Gerald P. Bodey; Boyd A. Nies; Emil Freireich

doi:10.1001/jama.1965.03090020019005

Causes of Death in Acute Leukemia: A Ten-Year Study of 414 Patients From 1954-1963

Evan M. Hersh
, Gerald P. Bodey
, Boyd A. Nies
, Emil Freireich

Cancer Center

Research output: Contribution to journal › Article › peer-review

337 Scopus citations

Abstract

Major causes of death in acute leukemia were infection in 70% of patients and hemorrhage in 52%. In 38% of the patients there was more than one cause of death. Striking changes took place during the ten-year-study period. Fatal hemorrhage declined to nearly half the early rate, and fatal staphylococcal infection from 23.5% to 3.1%. At the same time fatal infections due to fungi increased from 8.2% to 23.2%.

Original language	English (US)
Pages (from-to)	105-109
Number of pages	5
Journal	JAMA: The Journal of the American Medical Association
Volume	193
Issue number	2
DOIs	https://doi.org/10.1001/jama.1965.03090020019005
State	Published - Jul 12 1965

ASJC Scopus subject areas

General Medicine

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title = "Causes of Death in Acute Leukemia: A Ten-Year Study of 414 Patients From 1954-1963",

abstract = "Major causes of death in acute leukemia were infection in 70\% of patients and hemorrhage in 52\%. In 38\% of the patients there was more than one cause of death. Striking changes took place during the ten-year-study period. Fatal hemorrhage declined to nearly half the early rate, and fatal staphylococcal infection from 23.5\% to 3.1\%. At the same time fatal infections due to fungi increased from 8.2\% to 23.2\%.",

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AB - Major causes of death in acute leukemia were infection in 70% of patients and hemorrhage in 52%. In 38% of the patients there was more than one cause of death. Striking changes took place during the ten-year-study period. Fatal hemorrhage declined to nearly half the early rate, and fatal staphylococcal infection from 23.5% to 3.1%. At the same time fatal infections due to fungi increased from 8.2% to 23.2%.

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Causes of Death in Acute Leukemia: A Ten-Year Study of 414 Patients From 1954-1963

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