Catheter ablation of scar-based ventricular tachycardia: Relationship of procedure duration to outcomes and hospital mortality

Ricky Yu, Sootkeng Ma, Roderick Tung, Steven Stevens, Carlos Macias, Jason Bradfield, Eric Buch, Marmar Vaseghi, Osama Fujimura, Jeffrey Gornbein, Ravi Mandapati, Kalyanam Shivkumar, Noel G. Boyle

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

BACKGROUND: Ablation has become an important option for treatment of ventricular tachycardia (VT). The influence of procedure duration on outcomes remains unexamined. OBJECTIVE: The purpose of this study was to determine the influence of procedure duration on outcomes and complications over an 8-year period METHODS: Patients referred for scar-mediated VT ablation from 2004 to 2011 were retrospectively analyzed. Procedure duration was defined as the time from the insertion of catheters through the femoral vein to the time of their withdrawal. Procedure duration was analyzed in relationship with baseline and intraoperative covariates, acute procedural outcomes, complications, and 6-month clinical outcomes. RESULTS: One hundred forty-eight patients underwent VT ablation with mean procedure duration of 5.7 ± 1.8 hours. VT recurrence and survival at 6 months were 46% and 82%, respectively, and were not associated with procedure duration. Hospital mortality increased with intraoperative intraaortic balloon pump insertion (adjusted odds ratio [OR] 13.7, 95% confidence interval [CI] 2.35-79.94, P = .004) and was improved with successful ablation of the clinical VT as a procedural end-point (adjusted OR 0.13, 95% Cl 0.03-0.54, P = .005). The association between procedure duration and hospital mortality remained after adjusting for significant baseline variables (adjusted OR 1.75, 95% CI 1.14-2.68, P = .0098) and intraoperative variables (adjusted OR 1.6, 95% CI 1.12-2.29, P = .0104). CONCLUSION: Hospital mortality was significantly increased by unsuccessful clinical VT ablation as a procedural end-point and intraoperative intraaortic balloon pump insertion. However, after adjusting for significant baseline and intraoperative covariates, procedure duration still was associated with increased hospital mortality. Procedure duration had no impact on VT recurrence and survival at 6 months.

Original languageEnglish (US)
Pages (from-to)86-94
Number of pages9
JournalHeart Rhythm
Volume12
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Keywords

  • Hospital mortality
  • Procedure duration
  • Ventricular tachycardia
  • Ventricular tachycardia ablation
  • Ventricular tachycardia ablation efficacy
  • Ventricular tachycardia recurrence

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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