Abstract
Acid Showdown! The first catalytic ring expansion of vinyl oxetanes to 3,6-dihydro-2H-pyrans is described. Copper(II) triflate emerged as the best catalyst for this new transformation, which has broad scope as demonstrated by the eighteen examples included. The symmetric vinyl oxetane substrate can be asymmetrically desymmetrized when using either chiral Lewis or Brønsted acids as catalysts.
Original language | English (US) |
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Pages (from-to) | 5675-5678 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 51 |
Issue number | 23 |
DOIs | |
State | Published - Jun 4 2012 |
Keywords
- chiral counterions
- copper
- homogeneous catalysis
- ring expansion
- vinyl oxetanes
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)