Abstract
This highlight summarizes a recent development of a catalytic enantioselective Catellani-type reaction for the synthesis of axially chiral biaryls. The chirality induction is solely governed by chiral norbornene ligand in the Pd mediated ortho C–H functionalization and ipso cross-coupling transformation. The preparative power of the methodology is demonstrated as a powerful manifold for the divergent synthesis of structurally diverse axially chiral biaryls and chiral fluorenols.
Original language | English (US) |
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Pages (from-to) | 83-85 |
Number of pages | 3 |
Journal | Green Synthesis and Catalysis |
Volume | 1 |
Issue number | 2 |
DOIs | |
State | Published - Nov 2020 |
Keywords
- Asymmetric Catellani reaction
- Axially chiral biaryls
- Cross coupling
- C–H functionalization
- Divergent synthesis
ASJC Scopus subject areas
- Biotechnology
- Catalysis