Cardiocerebral resuscitation improves out-of-hospital survival in older adults

M. Jane Mohler, Christopher S. Wendel, Jarrod Mosier, Ajit Itty, Mindy Fain, Lani Clark, Bentley Bobrow, Arthur B. Sanders

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Objectives: To compare the survival and neurological status of people aged 65 and older receiving cardiocerebral resuscitation (CCR) with that of those receiving standard advanced life support (Std-ALS), as well as predictors of survival. Design: Historical prospective cohort study. Setting: The Save Hearts in Arizona Registry (SHARE). Participants: Persons who had experienced cardiac arrest receiving CCR or Std-ALS. Measurements: Patient demographics, emergency medical service events, survival to hospital discharge, and out-of-hospital cardiac arrest (OHCA) outcomes were obtained from Arizona hospital records and Bureau of Public Health Statistics from 2005 to 2008. Results: People receiving CCR were twice as likely to survive as those receiving Std-ALS (adjusted odds ratio=2.0, P=.005). An additional 20 per 1,000 older adults would survive, above the background survival rate of Std-ALS, if given CCR. More than 96% of those receiving CCR had good or moderate neurological outcomes, compared with 89% of those receiving Std.-ALS (P=.41). Conclusion: CCR is associated with superior survival outcomes than Std-ALS for OHCAs in people aged 65 and older. Use of CCR in older adults without known do-not-resuscitate status is warranted. These findings should be understood within the broader context of the essential role of comprehensive advance care planning in providing care consistent with patient goals and values.

Original languageEnglish (US)
Pages (from-to)822-826
Number of pages5
JournalJournal of the American Geriatrics Society
Issue number5
StatePublished - May 2011


  • CPR
  • EMS
  • aging
  • cardiac arrest
  • cardiocerebral resuscitation
  • geriatric

ASJC Scopus subject areas

  • Geriatrics and Gerontology


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