Cardenolides and a lignan from asclepias subulata

Shivanand D. Jolad, Robert B. Bates, Jack R. Cole, Joseph J. Hoffmann, Teruna J. Siahaan, Barbara N. Timmermann

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Four new glycosides (three cardenolides and a lignan), nine previously reported cardenolide glycosides and a known triterpenoid were isolated from the ethyl acetate extract of the aerial parts of Asclepias subulata. The elucidation of the structures and stereochemistry of the new glycosides has been accomplished using mainly 1H and 13C NMR and mass (EI and FAB) spectral data of their acetyl derivatives and comparison of these data with those of known glycosides from the same plant as well as from other plants. The new compounds were identified as 16α-hydroxycalactin, 3β-(β-D-glucopyranosyloxy)-19-car coroglaucigenin 3β-D-glucoside and 4-(β-D-glucopyranosyloxy)-larciresinol.

Original languageEnglish (US)
Pages (from-to)2581-2590
Number of pages10
Issue number11
StatePublished - 1986


  • Asclepiadaceae
  • Asclepias subulata
  • cardiac glycosides
  • larciresinol glucoside
  • lupeol.

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture


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