Carcinoma of the cervix: Deficiency of nexus intercellular junctions

N. Scott Mcnutt; Ronald S. Weinstein

doi:10.1126/science.165.3893.597

Carcinoma of the cervix: Deficiency of nexus intercellular junctions

N. Scott Mcnutt, Ronald S. Weinstein

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

Intercellar junctions where cell membranes are in intimate contact (nexuses) are very abundant in the epithelium of normal human cervix. Squamous carcinoma cells are deficient in nexuses although a rare nexus is seen. Nexuses may be involved in normal growth regulation, while a deficiency of nexuses may be related to the invasive property of malignant growth.

Original language	English (US)
Pages (from-to)	597-599
Number of pages	3
Journal	Science
Volume	165
Issue number	3893
DOIs	https://doi.org/10.1126/science.165.3893.597
State	Published - 1969
Externally published	Yes

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title = "Carcinoma of the cervix: Deficiency of nexus intercellular junctions",

abstract = "Intercellar junctions where cell membranes are in intimate contact (nexuses) are very abundant in the epithelium of normal human cervix. Squamous carcinoma cells are deficient in nexuses although a rare nexus is seen. Nexuses may be involved in normal growth regulation, while a deficiency of nexuses may be related to the invasive property of malignant growth.",

author = "Mcnutt, \{N. Scott\} and Weinstein, \{Ronald S.\}",

year = "1969",

doi = "10.1126/science.165.3893.597",

language = "English (US)",

volume = "165",

pages = "597--599",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

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T1 - Carcinoma of the cervix

T2 - Deficiency of nexus intercellular junctions

AU - Mcnutt, N. Scott

AU - Weinstein, Ronald S.

PY - 1969

Y1 - 1969

N2 - Intercellar junctions where cell membranes are in intimate contact (nexuses) are very abundant in the epithelium of normal human cervix. Squamous carcinoma cells are deficient in nexuses although a rare nexus is seen. Nexuses may be involved in normal growth regulation, while a deficiency of nexuses may be related to the invasive property of malignant growth.

AB - Intercellar junctions where cell membranes are in intimate contact (nexuses) are very abundant in the epithelium of normal human cervix. Squamous carcinoma cells are deficient in nexuses although a rare nexus is seen. Nexuses may be involved in normal growth regulation, while a deficiency of nexuses may be related to the invasive property of malignant growth.

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U2 - 10.1126/science.165.3893.597

DO - 10.1126/science.165.3893.597

M3 - Article

C2 - 5815840

AN - SCOPUS:0014668128

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SP - 597

EP - 599

JO - Science

JF - Science

IS - 3893

ER -

Carcinoma of the cervix: Deficiency of nexus intercellular junctions

Abstract

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