TY - JOUR
T1 - Cancer-related cognitive changes in children, adolescents and adult survivors of childhood cancers
AU - Ki Moore, Ida M.
AU - Hockenberry, Marilyn J.
AU - Krull, Kevin R.
PY - 2013/11
Y1 - 2013/11
N2 - Objectives: To summarize the current knowledge about 1) cognitive changes associated with central nervous system-directed chemotherapy and cranial radiation among children with acute lymphoblastic leukemia and brain tumors and adult survivors; and 2) interventions designed to prevent or remediate the cognitive and academic problems associated with central nervous system-directed cancer treatment. Data Sources: Classic and current databased publications. Conclusion: Future directions for research include 1) identification of sources of variability in long-term outcomes; 2) greater understanding of the developmental evolution of deficits across the survivor lifespan; and 3) interventions to treat and prevent negative outcomes following cancer therapy. Implications for Nursing Practice: Pediatric oncology nurses have a critical role in identifying children and adolescents at risk for cognitive changes associated with cancer therapy, initiating referral for assessment of cognitive changes during and after therapy, and advocating for resources to enhance cognitive and academic outcomes.
AB - Objectives: To summarize the current knowledge about 1) cognitive changes associated with central nervous system-directed chemotherapy and cranial radiation among children with acute lymphoblastic leukemia and brain tumors and adult survivors; and 2) interventions designed to prevent or remediate the cognitive and academic problems associated with central nervous system-directed cancer treatment. Data Sources: Classic and current databased publications. Conclusion: Future directions for research include 1) identification of sources of variability in long-term outcomes; 2) greater understanding of the developmental evolution of deficits across the survivor lifespan; and 3) interventions to treat and prevent negative outcomes following cancer therapy. Implications for Nursing Practice: Pediatric oncology nurses have a critical role in identifying children and adolescents at risk for cognitive changes associated with cancer therapy, initiating referral for assessment of cognitive changes during and after therapy, and advocating for resources to enhance cognitive and academic outcomes.
KW - Childhood and adult cancer survivors
KW - Cognitive interventions
KW - Cognitive late effects
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U2 - 10.1016/j.soncn.2013.08.005
DO - 10.1016/j.soncn.2013.08.005
M3 - Article
C2 - 24183156
AN - SCOPUS:84887206260
VL - 29
SP - 248
EP - 259
JO - Seminars in Oncology Nursing
JF - Seminars in Oncology Nursing
SN - 0749-2081
IS - 4
ER -