Calcium metabolism and dietary calcium in salt sensitive hypertension

James R. Sowers; Michael B. Zemel; Paula G. Zemel; Paul R. Standley

doi:10.1093/ajh/4.6.557

Calcium metabolism and dietary calcium in salt sensitive hypertension

James R. Sowers, Michael B. Zemel, Paula G. Zemel, Paul R. Standley

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Evidence has accumulated over the past decade that suggests a relationship between low calcium intake, abnormalities in cation metabolism and hypertension in certain segments of the essential hypertension population. This evidence has been developed from epidemiological data, calcium intervention trials and observations related to biochemical alterations suggestive of a calcium deficiency in certain patients with hypertension and in animal models of essential hypertension. It is becoming increasingly evident that salt sensitive individuals are especiallylikely to be characterized by abnormalities of calcium metabolism and blood pressure responses to dietary calcium. In this review the role of calcium in the regulation of blood pressure is examined with an emphasis on epidemiological, biochemical, hemodynamic and dietary intervention data in the salt sensitive hypertensive patient. Am J Hypertens 1991;4:557-563.

Original language	English (US)
Pages (from-to)	557-563
Number of pages	7
Journal	American Journal of Hypertension
Volume	4
Issue number	6
DOIs	https://doi.org/10.1093/ajh/4.6.557
State	Published - Mar 1991
Externally published	Yes

Keywords

Calcium
Hypertension
Salt sensitivity

ASJC Scopus subject areas

Internal Medicine

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10.1093/ajh/4.6.557

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AU - Sowers, James R.

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AU - Zemel, Paula G.

AU - Standley, Paul R.

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AB - Evidence has accumulated over the past decade that suggests a relationship between low calcium intake, abnormalities in cation metabolism and hypertension in certain segments of the essential hypertension population. This evidence has been developed from epidemiological data, calcium intervention trials and observations related to biochemical alterations suggestive of a calcium deficiency in certain patients with hypertension and in animal models of essential hypertension. It is becoming increasingly evident that salt sensitive individuals are especiallylikely to be characterized by abnormalities of calcium metabolism and blood pressure responses to dietary calcium. In this review the role of calcium in the regulation of blood pressure is examined with an emphasis on epidemiological, biochemical, hemodynamic and dietary intervention data in the salt sensitive hypertensive patient. Am J Hypertens 1991;4:557-563.

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Calcium metabolism and dietary calcium in salt sensitive hypertension

Abstract

Keywords

ASJC Scopus subject areas

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